BDBM494816 N-[(7S)-4- fluorobicyclo[4.2.0]octa-1,3,5- trien-7-yl]-N'-hydroxy-4-[(2- hydroxyethyl)amino]-1,2,5- oxadiazole-3-carboximidamide::US10988487, Example 212

SMILES: OCCNc1nonc1\C(N[C@H]1Cc2ccc(F)cc12)=N\O

InChI Key: InChIKey=VRSABBYATNSXOX-JTQLQIEISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 494816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human))	BDBM494816 (N-[(7S)-4- fluorobicyclo[4.2.0]octa-1,3,5- trien-7...) Show SMILES OCCNc1nonc1\C(N[C@H]1Cc2ccc(F)cc12)=N\O |r| Show InChI InChI=1S/C13H14FN5O3/c14-8-2-1-7-5-10(9(7)6-8)16-13(17-21)11-12(15-3-4-20)19-22-18-11/h1-2,6,10,20-21H,3-5H2,(H,15,19)(H,16,17)/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	57.8	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description HIS-tagged IDO1 protein was recombinantly expressed in Escherichia coli using ZYP5052 autoinduction media supplemented with 500 μM delta aminole...				US Patent US10988487 (2021)
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