null

SMILES: Cc1cc(Oc2ccc(cc2C)C(=O)N[C@H](CO)C(=O)N2[C@@H](CC[C@@H]2C(C)(C)C#N)c2cccc(Cl)c2)c(=O)[nH]n1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 495155   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM495155 (US10995084, Ex. No. 5C-1) Show SMILES Cc1cc(Oc2ccc(cc2C)C(=O)N[C@H](CO)C(=O)N2[C@@H](CC[C@@H]2C(C)(C)C#N)c2cccc(Cl)c2)c(=O)[nH]n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
KISSEI PHARMACEUTICAL CO., LTD. US Patent					Assay Description The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...				US Patent US10995084 (2021)
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM495155 (US10995084, Ex. No. 5C-1) Show SMILES Cc1cc(Oc2ccc(cc2C)C(=O)N[C@H](CO)C(=O)N2[C@@H](CC[C@@H]2C(C)(C)C#N)c2cccc(Cl)c2)c(=O)[nH]n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a	n/a
KISSEI PHARMACEUTICAL CO., LTD. US Patent					Assay Description The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...				US Patent US10995084 (2021)
					More data for this Ligand-Target Pair