US11001563, Compound WX111

SMILES: Cc1nc(sc1C)-c1ccc(OC\C(CN)=C/F)cc1

InChI Key: InChIKey=UOSIGUHTQCJDAG-GHXNOFRVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 497214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM497214 (US11001563, Compound WX111) Show SMILES Cc1nc(sc1C)-c1ccc(OC\C(CN)=C/F)cc1 Show InChI InChI=1S/C15H17FN2OS/c1-10-11(2)20-15(18-10)13-3-5-14(6-4-13)19-9-12(7-16)8-17/h3-7H,8-9,17H2,1-2H3/b12-7-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description The inhibition of the sample on VAP-enzyme activity was measured by using an Amplex® Red Monoamine Oxidase kit (Invitrogen #A12214). 100 nL of the gr...				US Patent US11001563 (2021)
					More data for this Ligand-Target Pair