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SMILES: CN(C)C1CCN(C1)c1ccc(N2CCC[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1

InChI Key: InChIKey=FUYKZUFXKPWSRS-FBLFFUNLSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 497408   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
fMet-Leu-Phe receptor


(Homo sapiens (Human))
BDBM497408
PNG
(US11008301, Example 81)
Show SMILES CN(C)C1CCN(C1)c1ccc(N2CCC[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1 |r|
Show InChI InChI=1S/C24H28ClF2N5O2/c1-30(2)17-9-11-31(14-17)16-6-8-22(19(27)13-16)32-10-3-4-21(23(32)33)29-24(34)28-20-7-5-15(25)12-18(20)26/h5-8,12-13,17,21H,3-4,9-11,14H2,1-2H3,(H2,28,29,34)/t17?,21-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.70E+3n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays. A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (...


US Patent US11008301 (2021)

More data for this
Ligand-Target Pair
N-formyl peptide receptor 2


(Homo sapiens (Human))
BDBM497408
PNG
(US11008301, Example 81)
Show SMILES CN(C)C1CCN(C1)c1ccc(N2CCC[C@@H](NC(=O)Nc3ccc(Cl)cc3F)C2=O)c(F)c1 |r|
Show InChI InChI=1S/C24H28ClF2N5O2/c1-30(2)17-9-11-31(14-17)16-6-8-22(19(27)13-16)32-10-3-4-21(23(32)33)29-24(34)28-20-7-5-15(25)12-18(20)26/h5-8,12-13,17,21H,3-4,9-11,14H2,1-2H3,(H2,28,29,34)/t17?,21-/m1/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 0.310n/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
FPR2 and FPR1 Cyclic Adenosine Monophosphate (cAMP) Assays. A mixture of forskolin (5 μM final for FPR2 or 10 μM final for FPR1) and IBMX (...


US Patent US11008301 (2021)

More data for this
Ligand-Target Pair