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SMILES: CC[C@@H](O)Cn1cc(cn1)-c1cncc(n1)[C@@]12CC[C@@H](c3cc(nnc13)-c1c(F)cccc1F)C2(C)C

InChI Key: InChIKey=FQAHCUXGHXWDTD-WCZIJOHHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 497559   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM497559
PNG
((2S)-1-[4-[6-[(1S,8R)-5-(2,6- difluorophenyl)-11,1...)
Show SMILES CC[C@@H](O)Cn1cc(cn1)-c1cncc(n1)[C@@]12CC[C@@H](c3cc(nnc13)-c1c(F)cccc1F)C2(C)C |r,TLB:24:25:18.17:34,21:20:18.17:34|
Show InChI InChI=1S/C28H28F2N6O/c1-4-17(37)15-36-14-16(11-32-36)23-12-31-13-24(33-23)28-9-8-19(27(28,2)3)18-10-22(34-35-26(18)28)25-20(29)6-5-7-21(25)30/h5-7,10-14,17,19,37H,4,8-9,15H2,1-3H3/t17-,19+,28+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.5n/an/an/an/an/an/a



Genentech, Inc.

US Patent


Assay Description
50 mM HEPES buffer (pH 7.4); 150 mM NaCl; 1 mM DTT; 5 mM MgCl2; 0.01% BSA; 5% DMSO; 0.6 ug/mL RORc receptor; 6 nM 25-[3H]hydroxycholesterol. For NSB ...

US Patent US11008312 (2021)

More data for this
Ligand-Target Pair