BDBM50000067 CHEMBL347514::[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(1-methyl-2-pyrrolidin-1-yl-ethyl)-amine
SMILES: C[C@@H](CN1CCCC1)N(C)CCc1ccc(Cl)c(Cl)c1
InChI Key: InChIKey=DBYCCKZCPWSDEM-ZDUSSCGKSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50000067 (CHEMBL347514 | [2-(3,4-Dichloro-phenyl)-ethyl]-met...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.620 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranes | J Med Chem 35: 38-47 (1992) BindingDB Entry DOI: 10.7270/Q2BP01RW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50000067 (CHEMBL347514 | [2-(3,4-Dichloro-phenyl)-ethyl]-met...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Ability of the compound to displace [3H]-sulpiride from dopamine receptor D2 in rat brain | J Med Chem 35: 38-47 (1992) BindingDB Entry DOI: 10.7270/Q2BP01RW | |||||||||||
More data for this Ligand-Target Pair |