BDBM50000218 CHEMBL143973

SMILES: C(Oc1ccccc1-c1cnccn1)C1=NCCN1

InChI Key: InChIKey=IJLWJFGTCGYKBI-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000218   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adrenergic alpha1B (Homo sapiens (Human))	BDBM50000218 (CHEMBL143973) Show SMILES C(Oc1ccccc1-c1cnccn1)C1=NCCN1 |t:16| Show InChI InChI=1S/C14H14N4O/c1-2-4-13(19-10-14-17-7-8-18-14)11(3-1)12-9-15-5-6-16-12/h1-6,9H,7-8,10H2,(H,17,18)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	631	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic, alpha-1B receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled P...				Bioorg Med Chem Lett 12: 471-5 (2002) Checked by Author BindingDB Entry DOI: 10.7270/Q22V2HD6
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50000218 (CHEMBL143973) Show SMILES C(Oc1ccccc1-c1cnccn1)C1=NCCN1 |t:16| Show InChI InChI=1S/C14H14N4O/c1-2-4-13(19-10-14-17-7-8-18-14)11(3-1)12-9-15-5-6-16-12/h1-6,9H,7-8,10H2,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic, alpha-1D receptor expressed in rat-1 fibroblasts assayed via calcium mobilization through Gq coupled PLC ...				Bioorg Med Chem Lett 12: 471-5 (2002) Checked by Author BindingDB Entry DOI: 10.7270/Q22V2HD6
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50000218 (CHEMBL143973) Show SMILES C(Oc1ccccc1-c1cnccn1)C1=NCCN1 |t:16| Show InChI InChI=1S/C14H14N4O/c1-2-4-13(19-10-14-17-7-8-18-14)11(3-1)12-9-15-5-6-16-12/h1-6,9H,7-8,10H2,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Activation of recombinant human adrenergic,alpha-1A receptor expressed in rat-1 fibroblasts determined via calcium mobilization through Gq coupled PL...				Bioorg Med Chem Lett 12: 471-5 (2002) Checked by Author BindingDB Entry DOI: 10.7270/Q22V2HD6
					More data for this Ligand-Target Pair