BDBM50000310 6-(2-Imidazol-1-yl-vinyl)-3,4-dihydro-1H-quinolin-2-one::CHEMBL160790

SMILES: O=C1CCc2cc(\C=C\n3ccnc3)ccc2N1

InChI Key: InChIKey=PERHUGCCUROAON-FNORWQNLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50000310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50000310 (6-(2-Imidazol-1-yl-vinyl)-3,4-dihydro-1H-quinolin-...) Show SMILES O=C1CCc2cc(\C=C\n3ccnc3)ccc2N1 Show InChI InChI=1S/C14H13N3O/c18-14-4-2-12-9-11(1-3-13(12)16-14)5-7-17-8-6-15-10-17/h1,3,5-10H,2,4H2,(H,16,18)/b7-5+	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of human blood platelet c-AMP phosphodiesterase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair
Thromboxane A2 Synthase (P450 TxA2) (Homo sapiens (Human))	BDBM50000310 (6-(2-Imidazol-1-yl-vinyl)-3,4-dihydro-1H-quinolin-...) Show SMILES O=C1CCc2cc(\C=C\n3ccnc3)ccc2N1 Show InChI InChI=1S/C14H13N3O/c18-14-4-2-12-9-11(1-3-13(12)16-14)5-7-17-8-6-15-10-17/h1,3,5-10H,2,4H2,(H,16,18)/b7-5+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Compound was evaluated for the inhibition of human blood platelet thromboxane A2 synthase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair