BDBM50000361 4-(3,4-Dimethoxy-phenyl)-1-(2-dimethylamino-ethyl)-3-methyl-6-trifluoromethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one::CHEMBL410539

SMILES: COc1ccc(cc1OC)[C@@H]1Cc2c(cccc2C(F)(F)F)N(CCN(C)C)C(=O)[C@@H]1C

InChI Key: InChIKey=FTETWFLTESHTEB-NVXWUHKLSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000361   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated L-type calcium channel (Homo sapiens (Human))	BDBM50000361 (4-(3,4-Dimethoxy-phenyl)-1-(2-dimethylamino-ethyl)...) Show SMILES COc1ccc(cc1OC)[C@@H]1Cc2c(cccc2C(F)(F)F)N(CCN(C)C)C(=O)[C@@H]1C Show InChI InChI=1S/C24H29F3N2O3/c1-15-17(16-9-10-21(31-4)22(13-16)32-5)14-18-19(24(25,26)27)7-6-8-20(18)29(23(15)30)12-11-28(2)3/h6-10,13,15,17H,11-12,14H2,1-5H3/t15-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro ability to displace the specific binding of [3H]-diltiazem to diltiazem receptor in guinea pig skeletal muscle.				J Med Chem 35: 780-93 (1992) BindingDB Entry DOI: 10.7270/Q2K64H14
					More data for this Ligand-Target Pair