BDBM50000382 CHEBI:6896::METIAMIDE::SK&F-92058

SMILES: C\N=C(/S)NCCSCc1[nH]cnc1C

InChI Key: InChIKey=FPBPLBWLMYGIQR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000382   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H2 receptor (RAT)	BDBM50000382 (CHEBI:6896 | METIAMIDE | SK&F-92058) Show SMILES C\N=C(/S)NCCSCc1[nH]cnc1C Show InChI InChI=1S/C9H16N4S2/c1-7-8(13-6-12-7)5-15-4-3-11-9(14)10-2/h6H,3-5H2,1-2H3,(H,12,13)(H2,10,11,14)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at histamine H2 receptor in Charles River rat assessed as inhibition of histamine-mediated electrically stimulated uterine contra...				J Med Chem 22: 301-6 (1979) BindingDB Entry DOI: 10.7270/Q25140QF
					More data for this Ligand-Target Pair