BDBM50000424 5-(4-Fluoro-phenylcarbamoyl)-pyridine-2-carboxylic acid::CHEMBL354140

SMILES: OC(=O)c1ccc(cn1)C(=O)Nc1ccc(F)cc1

InChI Key: InChIKey=OJKIZXCRAFZAAN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000424   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hypoxia-inducible factor prolyl hydroxylase 4 (HIF) (Homo sapiens (Human))	BDBM50000424 (5-(4-Fluoro-phenylcarbamoyl)-pyridine-2-carboxylic...) Show SMILES OC(=O)c1ccc(cn1)C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C13H9FN2O3/c14-9-2-4-10(5-3-9)16-12(17)8-1-6-11(13(18)19)15-7-8/h1-7H,(H,16,17)(H,18,19)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of prolyl 4-hydroxylase activity by an indirect assay				J Med Chem 35: 804-7 (1992) BindingDB Entry DOI: 10.7270/Q2FF3R9D
					More data for this Ligand-Target Pair