BDBM50000498 2-Amino-1,2,3,4-tetrahydro-naphthalene-1,6,7-triol::CHEMBL7185
SMILES: N[C@@H]1CCc2cc(O)c(O)cc2[C@H]1O
InChI Key: InChIKey=DTKDYAXITHKMGK-GMSGAONNSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50000498 (2-Amino-1,2,3,4-tetrahydro-naphthalene-1,6,7-triol...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Binding affinity towards Alpha-2 adrenergic receptor of rat brain | J Med Chem 35: 1009-18 (1992) BindingDB Entry DOI: 10.7270/Q2J38T5T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50000498 (2-Amino-1,2,3,4-tetrahydro-naphthalene-1,6,7-triol...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Binding affinity towards Alpha-1 adrenergic receptor of rat brain | J Med Chem 35: 1009-18 (1992) BindingDB Entry DOI: 10.7270/Q2J38T5T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ADRB2 (BOVINE) | BDBM50000498 (2-Amino-1,2,3,4-tetrahydro-naphthalene-1,6,7-triol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Compound was evaluated for beta adrenergic binding affinity towards Beta-2 adrenergic receptor of bovine lung | J Med Chem 35: 1009-18 (1992) BindingDB Entry DOI: 10.7270/Q2J38T5T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-1 adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50000498 (2-Amino-1,2,3,4-tetrahydro-naphthalene-1,6,7-triol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa Curated by ChEMBL | Assay Description Compound was evaluated for beta adrenergic binding affinity towards Beta-1 adrenergic receptor of rat brain | J Med Chem 35: 1009-18 (1992) BindingDB Entry DOI: 10.7270/Q2J38T5T | |||||||||||
More data for this Ligand-Target Pair |