BDBM50000706 6-{7-[4-(4-Fluoro-phenyl)-1-methyl-butyl]-5-methoxy-10,10-dimethyl-1,2,4,10-tetrahydro-9-oxa-3-aza-phenanthren-3-yl}-hexanoic acid::CHEMBL291432

SMILES: COc1cc(cc2OC(C)(C)C3=C(CN(CCCCCC(O)=O)CC3)c12)C(C)CCCc1ccc(F)cc1

InChI Key: InChIKey=LCGCRFOPZGGJNQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-activating factor receptor (Cavia porcellus)	BDBM50000706 (6-{7-[4-(4-Fluoro-phenyl)-1-methyl-butyl]-5-methox...) Show SMILES COc1cc(cc2OC(C)(C)C3=C(CN(CCCCCC(O)=O)CC3)c12)C(C)CCCc1ccc(F)cc1 |t:11| Show InChI InChI=1S/C32H42FNO4/c1-22(9-8-10-23-12-14-25(33)15-13-23)24-19-28(37-4)31-26-21-34(17-7-5-6-11-30(35)36)18-16-27(26)32(2,3)38-29(31)20-24/h12-15,19-20,22H,5-11,16-18,21H2,1-4H3,(H,35,36)	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro intrinsic binding affinity at platelet activating factor receptor using rabbit platelet membranes				J Med Chem 35: 2055-61 (1992) BindingDB Entry DOI: 10.7270/Q2NZ86K9
					More data for this Ligand-Target Pair