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SMILES: CNC(=O)CN1CCC(=C(C1)c1c(O)cc(cc1O)C(C)CCCc1ccc(F)cc1)C(C)(C)O

InChI Key: InChIKey=BRBLCPVLTMTIQM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000713   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-activating factor receptor


(Cavia porcellus)		BDBM50000713
PNG
(2-[5-{4-[4-(4-Fluoro-phenyl)-1-methyl-butyl]-2,6-d...)
Show SMILES CNC(=O)CN1CCC(=C(C1)c1c(O)cc(cc1O)C(C)CCCc1ccc(F)cc1)C(C)(C)O |c:8,(7.36,1.79,;6.01,1.02,;6.03,-.52,;7.36,-1.29,;4.7,-1.32,;4.7,-2.86,;3.38,-3.63,;3.38,-5.17,;4.7,-5.91,;6.03,-5.17,;6.03,-3.63,;7.36,-5.91,;7.36,-7.45,;6.03,-8.22,;8.67,-8.21,;10.01,-7.45,;9.99,-5.91,;8.67,-5.17,;8.67,-3.63,;11.34,-8.22,;11.34,-9.76,;12.67,-7.44,;14,-8.21,;15.34,-7.44,;16.66,-8.21,;16.66,-9.75,;18.01,-10.5,;19.35,-9.73,;20.67,-10.5,;19.33,-8.19,;18,-7.42,;3.35,-6.68,;3.34,-8.21,;2.03,-5.88,;2.02,-7.44,)|
Show InChI InChI=1S/C28H37FN2O4/c1-18(6-5-7-19-8-10-21(29)11-9-19)20-14-24(32)27(25(33)15-20)22-16-31(17-26(34)30-4)13-12-23(22)28(2,3)35/h8-11,14-15,18,32-33,35H,5-7,12-13,16-17H2,1-4H3,(H,30,34)
MMDB

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Similars
PubMed
 2.35E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
In vitro intrinsic binding affinity at platelet activating factor receptor using rabbit platelet membranes

J Med Chem 35: 2055-61 (1992)


BindingDB Entry DOI: 10.7270/Q2NZ86K9
More data for this
Ligand-Target Pair