BDBM50000868 CHEMBL88444::{Cyclohexyl-[4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-yloxy)-butyryl]-amino}-acetic acid ethyl ester

SMILES: CCOC(=O)CN(C1CCCCC1)C(=O)CCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1

InChI Key: InChIKey=KGPRGRZUQMYFDW-UHFFFAOYSA-N

Data: 2 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50000868   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purinergic receptor P2Y12 (Homo sapiens (Human))	BDBM50000868 (CHEMBL88444 | {Cyclohexyl-[4-(2-oxo-2,3-dihydro-1H...) Show SMILES CCOC(=O)CN(C1CCCCC1)C(=O)CCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1 Show InChI InChI=1S/C24H30N4O5/c1-2-32-22(30)15-28(17-7-4-3-5-8-17)21(29)9-6-12-33-18-10-11-19-16(13-18)14-20-23(25-19)27-24(31)26-20/h10-11,13-14,17H,2-9,12,15H2,1H3,(H2,25,26,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50000868 (CHEMBL88444 | {Cyclohexyl-[4-(2-oxo-2,3-dihydro-1H...) Show SMILES CCOC(=O)CN(C1CCCCC1)C(=O)CCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1 Show InChI InChI=1S/C24H30N4O5/c1-2-32-22(30)15-28(17-7-4-3-5-8-17)21(29)9-6-12-33-18-10-11-19-16(13-18)14-20-23(25-19)27-24(31)26-20/h10-11,13-14,17H,2-9,12,15H2,1H3,(H2,25,26,27,31)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human platelet PDE by inhibiting cyclic Adenosine monophosphate (cAMP) hydrolysis				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
Purinergic receptor P2Y12 (Homo sapiens (Human))	BDBM50000868 (CHEMBL88444 | {Cyclohexyl-[4-(2-oxo-2,3-dihydro-1H...) Show SMILES CCOC(=O)CN(C1CCCCC1)C(=O)CCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1 Show InChI InChI=1S/C24H30N4O5/c1-2-32-22(30)15-28(17-7-4-3-5-8-17)21(29)9-6-12-33-18-10-11-19-16(13-18)14-20-23(25-19)27-24(31)26-20/h10-11,13-14,17H,2-9,12,15H2,1H3,(H2,25,26,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50000868 (CHEMBL88444 | {Cyclohexyl-[4-(2-oxo-2,3-dihydro-1H...) Show SMILES CCOC(=O)CN(C1CCCCC1)C(=O)CCCOc1ccc2nc3[nH]c(=O)[nH]c3cc2c1 Show InChI InChI=1S/C24H30N4O5/c1-2-32-22(30)15-28(17-7-4-3-5-8-17)21(29)9-6-12-33-18-10-11-19-16(13-18)14-20-23(25-19)27-24(31)26-20/h10-11,13-14,17H,2-9,12,15H2,1H3,(H2,25,26,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human platelet PDE by inhibiting cyclic Guanosine monophosphate (cGMP) hydrolysis				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair