null

SMILES: O=C(CCCCc1ccc2nc3[nH]c(=O)[nH]c3cc2c1)NC12C[C@H]3C[C@H](C[C@H](C3)C1)C2

InChI Key: InChIKey=LHTCPUPSLZUZHR-ZWTKJYBESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000876   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50000876 (5-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-y...) Show SMILES O=C(CCCCc1ccc2nc3[nH]c(=O)[nH]c3cc2c1)NC12C[C@H]3C[C@H](C[C@H](C3)C1)C2 |TLB:28:23:30:27.29.26,28:27:30:23.22.24| Show InChI InChI=1S/C25H30N4O2/c30-22(29-25-12-16-7-17(13-25)9-18(8-16)14-25)4-2-1-3-15-5-6-20-19(10-15)11-21-23(26-20)28-24(31)27-21/h5-6,10-11,16-18H,1-4,7-9,12-14H2,(H,29,30)(H2,26,27,28,31)/t16-,17+,18-,25?	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
P2Y purinoceptor 12 (Homo sapiens (Human))	BDBM50000876 (5-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-y...) Show SMILES O=C(CCCCc1ccc2nc3[nH]c(=O)[nH]c3cc2c1)NC12C[C@H]3C[C@H](C[C@H](C3)C1)C2 |TLB:28:23:30:27.29.26,28:27:30:23.22.24| Show InChI InChI=1S/C25H30N4O2/c30-22(29-25-12-16-7-17(13-25)9-18(8-16)14-25)4-2-1-3-15-5-6-20-19(10-15)11-21-23(26-20)28-24(31)27-21/h5-6,10-11,16-18H,1-4,7-9,12-14H2,(H,29,30)(H2,26,27,28,31)/t16-,17+,18-,25?	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	960	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using Adenosine diphosphate (ADP) as activating agent in rabbit platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair
P2Y purinoceptor 12 (Homo sapiens (Human))	BDBM50000876 (5-(2-Oxo-2,3-dihydro-1H-imidazo[4,5-b]quinolin-7-y...) Show SMILES O=C(CCCCc1ccc2nc3[nH]c(=O)[nH]c3cc2c1)NC12C[C@H]3C[C@H](C[C@H](C3)C1)C2 |TLB:28:23:30:27.29.26,28:27:30:23.22.24| Show InChI InChI=1S/C25H30N4O2/c30-22(29-25-12-16-7-17(13-25)9-18(8-16)14-25)4-2-1-3-15-5-6-20-19(10-15)11-21-23(26-20)28-24(31)27-21/h5-6,10-11,16-18H,1-4,7-9,12-14H2,(H,29,30)(H2,26,27,28,31)/t16-,17+,18-,25?	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.26E+3	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet aggregation using adenosine diphosphate (ADP) as activating agent in human platelet rich plasma (PRP)				J Med Chem 35: 2672-87 (1992) BindingDB Entry DOI: 10.7270/Q2513X52
					More data for this Ligand-Target Pair