BDBM50001247 8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic acid ethyl ester::8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic acid ethyl ester; hydrochloride(0.2H2O)::CHEMBL552895::CHEMBL95108

SMILES: CCOC(=O)c1cnc2c(OC)cccc2c1Nc1ccccc1C

InChI Key: InChIKey=CRJUJZNGVQRIJL-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001247   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Na/K-ATPase (Sus scrofa (Pig))	BDBM50001247 (8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic ac...) Show SMILES CCOC(=O)c1cnc2c(OC)cccc2c1Nc1ccccc1C Show InChI InChI=1S/C20H20N2O3/c1-4-25-20(23)15-12-21-19-14(9-7-11-17(19)24-3)18(15)22-16-10-6-5-8-13(16)2/h5-12H,4H2,1-3H3,(H,21,22)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Research Ltd. Curated by ChEMBL					Assay Description Binding affinity of compound towards H+/K+ ATPase for activation was determined				J Med Chem 33: 527-33 (1990) BindingDB Entry DOI: 10.7270/Q2Z31XND
					More data for this Ligand-Target Pair
Potassium-transporting ATPase (Sus scrofa (Pig))	BDBM50001247 (8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic ac...) Show SMILES CCOC(=O)c1cnc2c(OC)cccc2c1Nc1ccccc1C Show InChI InChI=1S/C20H20N2O3/c1-4-25-20(23)15-12-21-19-14(9-7-11-17(19)24-3)18(15)22-16-10-6-5-8-13(16)2/h5-12H,4H2,1-3H3,(H,21,22)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	7.0	n/a
Smith Kline & French Research Ltd. Curated by ChEMBL					Assay Description Binding affinity of compound towards H+/K+ ATPase for activation was determined				J Med Chem 33: 527-33 (1990) BindingDB Entry DOI: 10.7270/Q2Z31XND
					More data for this Ligand-Target Pair
Potassium-transporting ATPase (Sus scrofa (Pig))	BDBM50001247 (8-Methoxy-4-o-tolylamino-quinoline-3-carboxylic ac...) Show SMILES CCOC(=O)c1cnc2c(OC)cccc2c1Nc1ccccc1C Show InChI InChI=1S/C20H20N2O3/c1-4-25-20(23)15-12-21-19-14(9-7-11-17(19)24-3)18(15)22-16-10-6-5-8-13(16)2/h5-12H,4H2,1-3H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Concentration required to inhibit the activity of gastric H+/K+ ATPase				J Med Chem 35: 3413-22 (1992) BindingDB Entry DOI: 10.7270/Q2CN74J2
					More data for this Ligand-Target Pair