BDBM50001268 5,7-Dichloro-4-hydroxy-3-(4-nitro-phenyl)-1H-quinolin-2-one::CHEMBL116814

SMILES: Oc1c(-c2ccc(cc2)[N+]([O-])=O)c(=O)[nH]c2cc(Cl)cc(Cl)c12

InChI Key: InChIKey=RVJGGXHSQRVBHL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50001268   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50001268 (5,7-Dichloro-4-hydroxy-3-(4-nitro-phenyl)-1H-quino...) Show SMILES Oc1c(-c2ccc(cc2)[N+]([O-])=O)c(=O)[nH]c2cc(Cl)cc(Cl)c12 Show InChI InChI=1S/C15H8Cl2N2O4/c16-8-5-10(17)13-11(6-8)18-15(21)12(14(13)20)7-1-3-9(4-2-7)19(22)23/h1-6H,(H2,18,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace strychnine-insensitive [3H]-glycine binding to rat cortical membranes.				J Med Chem 35: 3423-5 (1992) BindingDB Entry DOI: 10.7270/Q2RR1X68
					More data for this Ligand-Target Pair