new BindingDB logo
myBDB logout

BDBM50001732 CHEMBL3238097

SMILES: [O-][N+](=O)c1cccc(Nc2ccnc3[nH]c4ccccc4c23)c1

InChI Key: InChIKey=NSTVFNSHCSHEMC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50001732   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase BRK


(Homo sapiens (Human))
BDBM50001732
PNG
(CHEMBL3238097)
Show SMILES [O-][N+](=O)c1cccc(Nc2ccnc3[nH]c4ccccc4c23)c1
Show InChI InChI=1S/C17H12N4O2/c22-21(23)12-5-3-4-11(10-12)19-15-8-9-18-17-16(15)13-6-1-2-7-14(13)20-17/h1-10H,(H2,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.70n/an/an/an/an/an/a



Martin-Luther University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation counting


Bioorg Med Chem Lett 24: 1948-51 (2014)


Article DOI: 10.1016/j.bmcl.2014.03.002
BindingDB Entry DOI: 10.7270/Q2TM7CN0
More data for this
Ligand-Target Pair