BDBM50001744 CHEMBL3238095

SMILES: CCOc1cccc(Nc2ccnc3[nH]c4ccccc4c23)c1

InChI Key: InChIKey=TWXOUQDVFJSHLV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50001744   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BRK (Homo sapiens (Human))	BDBM50001744 (CHEMBL3238095) Show SMILES CCOc1cccc(Nc2ccnc3[nH]c4ccccc4c23)c1 Show InChI InChI=1S/C19H17N3O/c1-2-23-14-7-5-6-13(12-14)21-17-10-11-20-19-18(17)15-8-3-4-9-16(15)22-19/h3-12H,2H2,1H3,(H2,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of Brk (unknown origin) using [gamma-33P]-ATP after 60 mins by scintillation counting				Bioorg Med Chem Lett 24: 1948-51 (2014) Article DOI: 10.1016/j.bmcl.2014.03.002 BindingDB Entry DOI: 10.7270/Q2TM7CN0
					More data for this Ligand-Target Pair