BDBM50001804 1-(2-{4-[3-(4-Fluoro-phenyl)-4-methyl-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL342730

SMILES: Cc1cccc2n(cc(-c3ccc(F)cc3)c12)C1CCN(CCN2CCNC2=O)CC1

InChI Key: InChIKey=UFCWWRYYWMLFPE-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001804   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50001804 (1-(2-{4-[3-(4-Fluoro-phenyl)-4-methyl-indol-1-yl]-...) Show SMILES Cc1cccc2n(cc(-c3ccc(F)cc3)c12)C1CCN(CCN2CCNC2=O)CC1 Show InChI InChI=1S/C25H29FN4O/c1-18-3-2-4-23-24(18)22(19-5-7-20(26)8-6-19)17-30(23)21-9-12-28(13-10-21)15-16-29-14-11-27-25(29)31/h2-8,17,21H,9-16H2,1H3,(H,27,31)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-prazosin from Alpha-1 adrenergic receptor in whole rat brain membranes				J Med Chem 35: 4823-31 (1993) BindingDB Entry DOI: 10.7270/Q2BK1B8P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50001804 (1-(2-{4-[3-(4-Fluoro-phenyl)-4-methyl-indol-1-yl]-...) Show SMILES Cc1cccc2n(cc(-c3ccc(F)cc3)c12)C1CCN(CCN2CCNC2=O)CC1 Show InChI InChI=1S/C25H29FN4O/c1-18-3-2-4-23-24(18)22(19-5-7-20(26)8-6-19)17-30(23)21-9-12-28(13-10-21)15-16-29-14-11-27-25(29)31/h2-8,17,21H,9-16H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranes				J Med Chem 35: 4823-31 (1993) BindingDB Entry DOI: 10.7270/Q2BK1B8P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001804 (1-(2-{4-[3-(4-Fluoro-phenyl)-4-methyl-indol-1-yl]-...) Show SMILES Cc1cccc2n(cc(-c3ccc(F)cc3)c12)C1CCN(CCN2CCNC2=O)CC1 Show InChI InChI=1S/C25H29FN4O/c1-18-3-2-4-23-24(18)22(19-5-7-20(26)8-6-19)17-30(23)21-9-12-28(13-10-21)15-16-29-14-11-27-25(29)31/h2-8,17,21H,9-16H2,1H3,(H,27,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from Dopamine receptor D2 rat striatal membranes				J Med Chem 35: 4823-31 (1993) BindingDB Entry DOI: 10.7270/Q2BK1B8P
					More data for this Ligand-Target Pair