null

SMILES: Fc1ccc(cc1)-c1cn(C2CCN(CCN3CCNC3=O)CC2)c2ccc(cc12)C(F)(F)F

InChI Key: InChIKey=PNJBDZLOVISXIH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001815   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50001815 (1-(2-{4-[3-(4-Fluoro-phenyl)-5-trifluoromethyl-ind...) Show SMILES Fc1ccc(cc1)-c1cn(C2CCN(CCN3CCNC3=O)CC2)c2ccc(cc12)C(F)(F)F Show InChI InChI=1S/C25H26F4N4O/c26-19-4-1-17(2-5-19)22-16-33(23-6-3-18(15-21(22)23)25(27,28)29)20-7-10-31(11-8-20)13-14-32-12-9-30-24(32)34/h1-6,15-16,20H,7-14H2,(H,30,34)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-prazosin from Alpha-1 adrenergic receptor in whole rat brain membranes				J Med Chem 35: 4823-31 (1993) BindingDB Entry DOI: 10.7270/Q2BK1B8P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50001815 (1-(2-{4-[3-(4-Fluoro-phenyl)-5-trifluoromethyl-ind...) Show SMILES Fc1ccc(cc1)-c1cn(C2CCN(CCN3CCNC3=O)CC2)c2ccc(cc12)C(F)(F)F Show InChI InChI=1S/C25H26F4N4O/c26-19-4-1-17(2-5-19)22-16-33(23-6-3-18(15-21(22)23)25(27,28)29)20-7-10-31(11-8-20)13-14-32-12-9-30-24(32)34/h1-6,15-16,20H,7-14H2,(H,30,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranes				J Med Chem 35: 4823-31 (1993) BindingDB Entry DOI: 10.7270/Q2BK1B8P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001815 (1-(2-{4-[3-(4-Fluoro-phenyl)-5-trifluoromethyl-ind...) Show SMILES Fc1ccc(cc1)-c1cn(C2CCN(CCN3CCNC3=O)CC2)c2ccc(cc12)C(F)(F)F Show InChI InChI=1S/C25H26F4N4O/c26-19-4-1-17(2-5-19)22-16-33(23-6-3-18(15-21(22)23)25(27,28)29)20-7-10-31(11-8-20)13-14-32-12-9-30-24(32)34/h1-6,15-16,20H,7-14H2,(H,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from Dopamine receptor D2 rat striatal membranes				J Med Chem 35: 4823-31 (1993) BindingDB Entry DOI: 10.7270/Q2BK1B8P
					More data for this Ligand-Target Pair