BDBM50001849 2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-1-[2-(3-phenyl-propoxymethyl)-piperidin-1-yl]-propan-1-one::CHEMBL307595

SMILES: Cc1cc(O)cc(C)c1CC(N)C(=O)N1CCCCC1COCCCc1ccccc1

InChI Key: InChIKey=KHTHDTHIFBMWBR-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50001849   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50001849 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-1-[2-(3-...) Show SMILES Cc1cc(O)cc(C)c1CC(N)C(=O)N1CCCCC1COCCCc1ccccc1 Show InChI InChI=1S/C26H36N2O3/c1-19-15-23(29)16-20(2)24(19)17-25(27)26(30)28-13-7-6-12-22(28)18-31-14-8-11-21-9-4-3-5-10-21/h3-5,9-10,15-16,22,25,29H,6-8,11-14,17-18,27H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle and Company Curated by ChEMBL					Assay Description Binding ability towards opioid receptor kappa expressed in homogenates of rat brain.				J Med Chem 35: 223-33 (1992) BindingDB Entry DOI: 10.7270/Q26T0KKD
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001849 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-1-[2-(3-...) Show SMILES Cc1cc(O)cc(C)c1CC(N)C(=O)N1CCCCC1COCCCc1ccccc1 Show InChI InChI=1S/C26H36N2O3/c1-19-15-23(29)16-20(2)24(19)17-25(27)26(30)28-13-7-6-12-22(28)18-31-14-8-11-21-9-4-3-5-10-21/h3-5,9-10,15-16,22,25,29H,6-8,11-14,17-18,27H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle and Company Curated by ChEMBL					Assay Description Binding ability towards opioid receptor mu expressed in homogenates of rat brain.				J Med Chem 35: 223-33 (1992) BindingDB Entry DOI: 10.7270/Q26T0KKD
					More data for this Ligand-Target Pair
Opioid receptors; mu & delta (Rattus norvegicus (rat))	BDBM50001849 (2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-1-[2-(3-...) Show SMILES Cc1cc(O)cc(C)c1CC(N)C(=O)N1CCCCC1COCCCc1ccccc1 Show InChI InChI=1S/C26H36N2O3/c1-19-15-23(29)16-20(2)24(19)17-25(27)26(30)28-13-7-6-12-22(28)18-31-14-8-11-21-9-4-3-5-10-21/h3-5,9-10,15-16,22,25,29H,6-8,11-14,17-18,27H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle and Company Curated by ChEMBL					Assay Description Binding ability towards opioid receptor delta expressed in homogenates of rat brain.				J Med Chem 35: 223-33 (1992) BindingDB Entry DOI: 10.7270/Q26T0KKD
					More data for this Ligand-Target Pair