BDBM50001878 1-{1-Methyl-5-[4-(2-propyl-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one::CHEMBL348014

SMILES: CCCc1ccccc1N1CCN(Cc2ccc(CN3CCCC3=O)n2C)CC1

InChI Key: InChIKey=VFYIFYPQQPJZIN-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50001878   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001878 (1-{1-Methyl-5-[4-(2-propyl-phenyl)-piperazin-1-ylm...) Show SMILES CCCc1ccccc1N1CCN(Cc2ccc(CN3CCCC3=O)n2C)CC1 Show InChI InChI=1S/C24H34N4O/c1-3-7-20-8-4-5-9-23(20)27-16-14-26(15-17-27)18-21-11-12-22(25(21)2)19-28-13-6-10-24(28)29/h4-5,8-9,11-12H,3,6-7,10,13-19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Binding affinity towards dopamine receptor D2 by displacing [3H]spiperone radioligand in rat striatum				J Med Chem 35: 552-8 (1992) BindingDB Entry DOI: 10.7270/Q2PR7WMW
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001878 (1-{1-Methyl-5-[4-(2-propyl-phenyl)-piperazin-1-ylm...) Show SMILES CCCc1ccccc1N1CCN(Cc2ccc(CN3CCCC3=O)n2C)CC1 Show InChI InChI=1S/C24H34N4O/c1-3-7-20-8-4-5-9-23(20)27-16-14-26(15-17-27)18-21-11-12-22(25(21)2)19-28-13-6-10-24(28)29/h4-5,8-9,11-12H,3,6-7,10,13-19H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]WB-4101 radioligand in rat cerebral cortex				J Med Chem 35: 552-8 (1992) BindingDB Entry DOI: 10.7270/Q2PR7WMW
					More data for this Ligand-Target Pair
Serotonin 1 (5-HT1) receptor (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50001878 (1-{1-Methyl-5-[4-(2-propyl-phenyl)-piperazin-1-ylm...) Show SMILES CCCc1ccccc1N1CCN(Cc2ccc(CN3CCCC3=O)n2C)CC1 Show InChI InChI=1S/C24H34N4O/c1-3-7-20-8-4-5-9-23(20)27-16-14-26(15-17-27)18-21-11-12-22(25(21)2)19-28-13-6-10-24(28)29/h4-5,8-9,11-12H,3,6-7,10,13-19H2,1-2H3	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	283	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortex				J Med Chem 35: 552-8 (1992) BindingDB Entry DOI: 10.7270/Q2PR7WMW
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50001878 (1-{1-Methyl-5-[4-(2-propyl-phenyl)-piperazin-1-ylm...) Show SMILES CCCc1ccccc1N1CCN(Cc2ccc(CN3CCCC3=O)n2C)CC1 Show InChI InChI=1S/C24H34N4O/c1-3-7-20-8-4-5-9-23(20)27-16-14-26(15-17-27)18-21-11-12-22(25(21)2)19-28-13-6-10-24(28)29/h4-5,8-9,11-12H,3,6-7,10,13-19H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	317	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards 5-hydroxytryptamine 2 receptor by displacing [3H]ketanserin radioligand in rat cerebral cort...				J Med Chem 35: 552-8 (1992) BindingDB Entry DOI: 10.7270/Q2PR7WMW
					More data for this Ligand-Target Pair