BDBM50001901 1-(2-Chloro-phenyl)-piperazine::CHEMBL9841

SMILES: Clc1ccccc1N1CCNCC1

InChI Key: InChIKey=PWZDJIUQHUGFRJ-UHFFFAOYSA-N

Data: 11 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50001901   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 1B/1D receptor (Rattus norvegicus (Rat))	BDBM50001901 (1-(2-Chloro-phenyl)-piperazine | CHEMBL9841) Show SMILES Clc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity at rat 5-hydroxytryptamine 1B receptor by [3H]-5-HT displacement.				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50001901 (1-(2-Chloro-phenyl)-piperazine | CHEMBL9841) Show SMILES Clc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity at rat 5-hydroxytryptamine 1A receptor by [3H]-WB-4101 displacement.				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
Serotonin 1 (5-HT1) receptor (RAT-Rattus norvegicus (rat)-Rattus norvegicus (Rat...)	BDBM50001901 (1-(2-Chloro-phenyl)-piperazine | CHEMBL9841) Show SMILES Clc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity in radioreceptor binding assay by using [3H]5-HT radioligand against 5-hydroxytryptamine 1 receptor				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
adrenergic Alpha2 (BOVINE)	BDBM50001901 (1-(2-Chloro-phenyl)-piperazine | CHEMBL9841) Show SMILES Clc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	KEGG GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding activity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]-clonidine as the radioligand				J Med Chem 26: 1696-701 (1984) BindingDB Entry DOI: 10.7270/Q2251H67
					More data for this Ligand-Target Pair
Cerebral cortex alpha adrenergic receptor (CALF)	BDBM50001901 (1-(2-Chloro-phenyl)-piperazine | CHEMBL9841) Show SMILES Clc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding activity against alpha-1 adrenergic receptor from calf cerebral cortex, using [3H]-prazosin as the radioligand				J Med Chem 26: 1696-701 (1984) BindingDB Entry DOI: 10.7270/Q2251H67
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50001901 (1-(2-Chloro-phenyl)-piperazine | CHEMBL9841) Show SMILES Clc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	226	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitá di Catania Curated by ChEMBL					Assay Description Binding affinity for 5-HT1A measured by displacing [3H]-8-OH-DPAT from rat cortical membranes; Not determined				J Med Chem 34: 1850-4 (1991) BindingDB Entry DOI: 10.7270/Q25B01FV
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50001901 (1-(2-Chloro-phenyl)-piperazine | CHEMBL9841) Show SMILES Clc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	261	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity in radioreceptor binding against Alpha-1 adrenergic receptor				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50001901 (1-(2-Chloro-phenyl)-piperazine | CHEMBL9841) Show SMILES Clc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universitá di Catania Curated by ChEMBL					Assay Description Binding affinity measured for alpha-1 adrenergic receptor by displacement of [3H]-prazosin from rat cortical membranes				J Med Chem 34: 1850-4 (1991) BindingDB Entry DOI: 10.7270/Q25B01FV
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001901 (1-(2-Chloro-phenyl)-piperazine | CHEMBL9841) Show SMILES Clc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity determined in radioreceptor binding assay against dopamine receptor D2				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50001901 (1-(2-Chloro-phenyl)-piperazine | CHEMBL9841) Show SMILES Clc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity determined in radioreceptor binding assay by using [3H]-SCH-23,390 radioligand against dopamine receptor D1				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50001901 (1-(2-Chloro-phenyl)-piperazine | CHEMBL9841) Show SMILES Clc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
McNeil Pharmaceutical and Janssen Research Foundation Worldwide Curated by ChEMBL					Assay Description Binding affinity at rat 5-hydroxytryptamine 2 receptor by [3H]ketanserin displacement.				J Med Chem 32: 1052-6 (1989) BindingDB Entry DOI: 10.7270/Q2HD7TNH
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Canis familiaris)	BDBM50001901 (1-(2-Chloro-phenyl)-piperazine | CHEMBL9841) Show SMILES Clc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Laboratories Curated by ChEMBL					Assay Description Binding affinity towards Beta-2 adrenergic receptor by displacing [3H]dihydroalprenolol, in partially purified membrane fractions from canine lung ti...				J Med Chem 35: 743-50 (1992) BindingDB Entry DOI: 10.7270/Q2319TT0
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50001901 (1-(2-Chloro-phenyl)-piperazine | CHEMBL9841) Show SMILES Clc1ccccc1N1CCNCC1 Show InChI InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Laboratories Curated by ChEMBL					Assay Description Binding affinity for Beta-1 adrenergic receptor by displacing [3H]dihydroalprenolol, in partially purified membrane fractions from canine ventricular...				J Med Chem 35: 743-50 (1992) BindingDB Entry DOI: 10.7270/Q2319TT0
					More data for this Ligand-Target Pair