BDBM50001942 CHEMBL2113668::Iodo-MLA
SMILES: [H][C@]12C[C@]3([H])[C@]([H])([C@H]1OC)[C@](O)(C[C@@H]2OC)[C@]1(O)[C@@H](OC)[C@@]2([H])[C@@]33[C@H](CC[C@@]2(COC(=O)c2cc([125I])ccc2N2C(=O)C[C@H](C)C2=O)CN(CC)[C@@]13[H])OC
InChI Key: InChIKey=YMDRDNRMRZWDNG-INMQOWSXSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Neuronal acetylcholine receptor (Rattus norvegicus (Rat)) | BDBM50001942 (CHEMBL2113668 | Iodo-MLA) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Inhibition of [125I]iodo-MLA binding in presence of alpha-bungarotoxin | J Med Chem 43: 142-5 (2000) Article DOI: 10.1021/jm990544f BindingDB Entry DOI: 10.7270/Q2G163KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor (Rattus norvegicus (Rat)) | BDBM50001942 (CHEMBL2113668 | Iodo-MLA) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Inhibition of [125I]iodo-MLA binding in presence of methylcaconitine. | J Med Chem 43: 142-5 (2000) Article DOI: 10.1021/jm990544f BindingDB Entry DOI: 10.7270/Q2G163KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor (Rattus norvegicus (Rat)) | BDBM50001942 (CHEMBL2113668 | Iodo-MLA) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Inhibition of [125I]iodo-MLA binding in presence of 3-cinnamylidene-anabasine | J Med Chem 43: 142-5 (2000) Article DOI: 10.1021/jm990544f BindingDB Entry DOI: 10.7270/Q2G163KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor (Rattus norvegicus (Rat)) | BDBM50001942 (CHEMBL2113668 | Iodo-MLA) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 667 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Inhibition of [125I]iodo-MLA binding in presence of (-)-nicotine | J Med Chem 43: 142-5 (2000) Article DOI: 10.1021/jm990544f BindingDB Entry DOI: 10.7270/Q2G163KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor (Rattus norvegicus (Rat)) | BDBM50001942 (CHEMBL2113668 | Iodo-MLA) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Inhibition of [125I]iodo-MLA binding in presence of mecamylamine | J Med Chem 43: 142-5 (2000) Article DOI: 10.1021/jm990544f BindingDB Entry DOI: 10.7270/Q2G163KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor (Rattus norvegicus (Rat)) | BDBM50001942 (CHEMBL2113668 | Iodo-MLA) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Inhibition of [125I]iodo-MLA binding in presence of dihydro-beta-erythroidine | J Med Chem 43: 142-5 (2000) Article DOI: 10.1021/jm990544f BindingDB Entry DOI: 10.7270/Q2G163KF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor (Rattus norvegicus (Rat)) | BDBM50001942 (CHEMBL2113668 | Iodo-MLA) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Dissociation constant for rat Nicotinic acetylcholine receptor alpha-7 at 45 pM | J Med Chem 48: 1221-8 (2005) Article DOI: 10.1021/jm040160b BindingDB Entry DOI: 10.7270/Q26W9BV6 | |||||||||||
More data for this Ligand-Target Pair |