BDBM50001948 2-(3,7-Diamino-2-hydroxy-heptanoylamino)-3-(1H-indol-3-yl)-propionic acid methyl ester::CHEMBL352473::Protein kinase C, PKC; classical

SMILES: COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](O)[C@@H](N)CCCCN

InChI Key: InChIKey=CGMUBURMPMVFHE-USXIJHARSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50001948   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Rattus norvegicus)	BDBM50001948 (2-(3,7-Diamino-2-hydroxy-heptanoylamino)-3-(1H-ind...) Show SMILES COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](O)[C@@H](N)CCCCN Show InChI InChI=1S/C19H28N4O4/c1-27-19(26)16(10-12-11-22-15-8-3-2-6-13(12)15)23-18(25)17(24)14(21)7-4-5-9-20/h2-3,6,8,11,14,16-17,22,24H,4-5,7,9-10,20-21H2,1H3,(H,23,25)/t14-,16+,17+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory potency against purified membrane bound rat brain Aminopeptidase M using [3H]Leu-enkephalin as substrate				J Med Chem 35: 889-95 (1992) BindingDB Entry DOI: 10.7270/Q2X92BWN
					More data for this Ligand-Target Pair
Aminopeptidase B (Rattus norvegicus)	BDBM50001948 (2-(3,7-Diamino-2-hydroxy-heptanoylamino)-3-(1H-ind...) Show SMILES COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](O)[C@@H](N)CCCCN Show InChI InChI=1S/C19H28N4O4/c1-27-19(26)16(10-12-11-22-15-8-3-2-6-13(12)15)23-18(25)17(24)14(21)7-4-5-9-20/h2-3,6,8,11,14,16-17,22,24H,4-5,7,9-10,20-21H2,1H3,(H,23,25)/t14-,16+,17+/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory potency against purified membrane bound rat brain Aminopeptidase B using L-lysine-beta napthylamide as subs...				J Med Chem 35: 889-95 (1992) BindingDB Entry DOI: 10.7270/Q2X92BWN
					More data for this Ligand-Target Pair