BDBM50001989 1-(4-Fluoro-phenyl)-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole::CHEMBL417614

SMILES: CN1CCC(=CC1)c1cn(-c2ccc(F)cc2)c2ccccc12

InChI Key: InChIKey=QVTIYLFSBMCCJG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50001989   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001989 (1-(4-Fluoro-phenyl)-3-(1-methyl-1,2,3,6-tetrahydro...) Show SMILES CN1CCC(=CC1)c1cn(-c2ccc(F)cc2)c2ccccc12 |c:4| Show InChI InChI=1S/C20H19FN2/c1-22-12-10-15(11-13-22)19-14-23(17-8-6-16(21)7-9-17)20-5-3-2-4-18(19)20/h2-10,14H,11-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Tested for the inhibition of [3H]-spiperone binding to dopamine D2 receptor				J Med Chem 35: 1092-101 (1992) BindingDB Entry DOI: 10.7270/Q2Z89BB3
					More data for this Ligand-Target Pair