BDBM50001997 1-(2-{4-[1-(4-Fluoro-phenyl)-5-trifluoromethyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL12910

SMILES: Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(ccc12)C(F)(F)F

InChI Key: InChIKey=WYZQZAVJYFIRQK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50001997   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50001997 (1-(2-{4-[1-(4-Fluoro-phenyl)-5-trifluoromethyl-1H-...) Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(ccc12)C(F)(F)F Show InChI InChI=1S/C25H26F4N4O/c26-19-2-4-20(5-3-19)33-16-22(21-15-18(25(27,28)29)1-6-23(21)33)17-7-10-31(11-8-17)13-14-32-12-9-30-24(32)34/h1-6,15-17H,7-14H2,(H,30,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Inhibition of [3H]ketanserin binding to rat 5-hydroxytryptamine 2 receptors.				J Med Chem 35: 1092-101 (1992) BindingDB Entry DOI: 10.7270/Q2Z89BB3
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001997 (1-(2-{4-[1-(4-Fluoro-phenyl)-5-trifluoromethyl-1H-...) Show SMILES Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(ccc12)C(F)(F)F Show InChI InChI=1S/C25H26F4N4O/c26-19-2-4-20(5-3-19)33-16-22(21-15-18(25(27,28)29)1-6-23(21)33)17-7-10-31(11-8-17)13-14-32-12-9-30-24(32)34/h1-6,15-17H,7-14H2,(H,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Tested for the inhibition of [3H]-spiperone binding to dopamine D2 receptor				J Med Chem 35: 1092-101 (1992) BindingDB Entry DOI: 10.7270/Q2Z89BB3
					More data for this Ligand-Target Pair