BDBM50002001 1-(2-{4-[5-Fluoro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL269679
SMILES: Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(F)ccc12
InChI Key: InChIKey=UEWDNBBZGQGYEW-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50002001 (1-(2-{4-[5-Fluoro-1-(4-fluoro-phenyl)-1H-indol-3-y...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.480 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S Curated by ChEMBL | Assay Description Inhibition of [3H]ketanserin binding to rat 5-hydroxytryptamine 2 receptors. | J Med Chem 35: 1092-101 (1992) BindingDB Entry DOI: 10.7270/Q2Z89BB3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50002001 (1-(2-{4-[5-Fluoro-1-(4-fluoro-phenyl)-1H-indol-3-y...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S Curated by ChEMBL | Assay Description Tested for the inhibition of [3H]-spiperone binding to dopamine D2 receptor | J Med Chem 35: 1092-101 (1992) BindingDB Entry DOI: 10.7270/Q2Z89BB3 | |||||||||||
More data for this Ligand-Target Pair |