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BDBM50002100 11-(3-Diethylamino-propylidene)-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid; compound with but-2-enedioic acid::CHEMBL63596

SMILES: CCN(CC)CC\C=C1\c2ccccc2COc2ccc(cc12)C(O)=O

InChI Key: InChIKey=SAXXMFGUIXYWRS-GRSHGNNSSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50002100   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H1 receptor


(Cavia porcellus (domestic guinea pig))		BDBM50002100
PNG
(11-(3-Diethylamino-propylidene)-6,11-dihydro-diben...)
Show SMILES CCN(CC)CC\C=C1\c2ccccc2COc2ccc(cc12)C(O)=O
Show InChI InChI=1S/C22H25NO3/c1-3-23(4-2)13-7-10-19-18-9-6-5-8-17(18)15-26-21-12-11-16(22(24)25)14-20(19)21/h5-6,8-12,14H,3-4,7,13,15H2,1-2H3,(H,24,25)/b19-10-
UniProtKB/SwissProt

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Similars
PubMed
 10n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Binding affinity for histamine H1 receptor from guinea pig cerebellum, using [3H]pyrilamine as radioligand at 0.1 uM

J Med Chem 35: 2074-84 (1992)


BindingDB Entry DOI: 10.7270/Q2N87BC0
More data for this
Ligand-Target Pair