BDBM50002175 6-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::CHEMBL130659

SMILES: COc1ccc2c(CCCCN3CCC(=CC3)c3ccccc3)c[nH]c2c1

InChI Key: InChIKey=PUZDYVQNYUCMKE-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50002175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002175 (6-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-...) Show SMILES COc1ccc2c(CCCCN3CCC(=CC3)c3ccccc3)c[nH]c2c1 |c:14| Show InChI InChI=1S/C24H28N2O/c1-27-22-10-11-23-21(18-25-24(23)17-22)9-5-6-14-26-15-12-20(13-16-26)19-7-3-2-4-8-19/h2-4,7-8,10-12,17-18,25H,5-6,9,13-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002175 (6-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-...) Show SMILES COc1ccc2c(CCCCN3CCC(=CC3)c3ccccc3)c[nH]c2c1 |c:14| Show InChI InChI=1S/C24H28N2O/c1-27-22-10-11-23-21(18-25-24(23)17-22)9-5-6-14-26-15-12-20(13-16-26)19-7-3-2-4-8-19/h2-4,7-8,10-12,17-18,25H,5-6,9,13-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes 3[H]spiperone, a dopamine antagonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair