BDBM50002654 (2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-(2-ethoxy-benzyl)-amine::CHEMBL89652
SMILES: CCOc1ccccc1CN[C@H]1C2CCN(CC2)[C@H]1C(c1ccccc1)c1ccccc1
InChI Key: InChIKey=GPUOQABHPXXQED-VMPREFPWSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Neurokinin 1 receptor (Homo sapiens (Human)) | BDBM50002654 ((2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-(2-eth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer, Inc. Curated by ChEMBL | Assay Description Binding affinity towards Tachykinin receptor 1 in human IM-9 cells using [3H]-substance P as ligand | J Med Chem 35: 2591-600 (1992) BindingDB Entry DOI: 10.7270/Q2SJ1JJF | |||||||||||
More data for this Ligand-Target Pair |