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BDBM50002798 CHEMBL114798::{11-[2-(5,6-Dimethyl-benzoimidazol-1-yl)-ethylidene]-6,11-dihydro-dibenzo[b,e]oxepin-2-yl}-acetic acid

SMILES: Cc1cc2ncn(C\C=C3/c4ccccc4COc4ccc(CC(O)=O)cc34)c2cc1C

InChI Key: InChIKey=KRGDODMQPWYVPR-LSFURLLWSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50002798   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostanoid TP receptor


(Homo sapiens (Human))		BDBM50002798
PNG
(CHEMBL114798 | {11-[2-(5,6-Dimethyl-benzoimidazol-...)
Show SMILES Cc1cc2ncn(C\C=C3/c4ccccc4COc4ccc(CC(O)=O)cc34)c2cc1C
Show InChI InChI=1S/C27H24N2O3/c1-17-11-24-25(12-18(17)2)29(16-28-24)10-9-22-21-6-4-3-5-20(21)15-32-26-8-7-19(13-23(22)26)14-27(30)31/h3-9,11-13,16H,10,14-15H2,1-2H3,(H,30,31)/b22-9+
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PC sid
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Similars
PubMed
 63n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity at TXA2/PGH2 receptor by measuring its ability to displace [3H]-U-46,619 from guinea pig platelets

J Med Chem 35: 3402-13 (1992)


BindingDB Entry DOI: 10.7270/Q2J38RG1
More data for this
Ligand-Target Pair