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BDBM50002810 11-[2-(4-Methyl-benzoimidazol-1-yl)-ethylidene]-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid::CHEMBL117242

SMILES: Cc1cccc2n(C\C=C3/c4ccccc4COc4ccc(cc34)C(O)=O)cnc12

InChI Key: InChIKey=NWUOFRGIKCBVLX-RGVLZGJSSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50002810   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostanoid TP receptor


(Homo sapiens (Human))		BDBM50002810
PNG
(11-[2-(4-Methyl-benzoimidazol-1-yl)-ethylidene]-6,...)
Show SMILES Cc1cccc2n(C\C=C3/c4ccccc4COc4ccc(cc34)C(O)=O)cnc12
Show InChI InChI=1S/C25H20N2O3/c1-16-5-4-8-22-24(16)26-15-27(22)12-11-20-19-7-3-2-6-18(19)14-30-23-10-9-17(25(28)29)13-21(20)23/h2-11,13,15H,12,14H2,1H3,(H,28,29)/b20-11+
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PubMed
 17n/an/an/an/an/an/an/an/a



Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity at TXA2/PGH2 receptor by measuring its ability to displace [3H]-U-46,619 from guinea pig platelets

J Med Chem 35: 3402-13 (1992)


BindingDB Entry DOI: 10.7270/Q2J38RG1
More data for this
Ligand-Target Pair