BDBM50002831 (2R,5R)-2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan::(2S,5S)-2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan::(E)-(1R,2R,3R,5R,12S,13R,16S)-16-Hydroxymethyl-5,9,12,13-tetramethyl-4-oxa-tricyclo[10.3.1.0*3,5*]hexadec-8-en-2-ol::(L 652731)2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan::2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan::2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan(L-652,731)::2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan(L-652731)::CHEMBL297624::L-652731

SMILES: COc1cc(cc(OC)c1OC)[C@@H]1CC[C@H](O1)c1cc(OC)c(OC)c(OC)c1

InChI Key: InChIKey=YCCPYTPBHUIHGW-HOTGVXAUSA-N

Data: 2 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50002831   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet activating factor receptor (Homo sapiens (Human))	BDBM50002831 ((2R,5R)-2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahyd...) Show SMILES COc1cc(cc(OC)c1OC)[C@@H]1CC[C@H](O1)c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C22H28O7/c1-23-17-9-13(10-18(24-2)21(17)27-5)15-7-8-16(29-15)14-11-19(25-3)22(28-6)20(12-14)26-4/h9-12,15-16H,7-8H2,1-6H3/t15-,16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	215	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rhone-Poulenc Sante Curated by PDSP Ki Database									J Pharmacol Exp Ther 252: 1221-7 (1990) BindingDB Entry DOI: 10.7270/Q2JW8CC2
					More data for this Ligand-Target Pair
Platelet activating factor receptor (Homo sapiens (Human))	BDBM50002831 ((2R,5R)-2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahyd...) Show SMILES COc1cc(cc(OC)c1OC)[C@@H]1CC[C@H](O1)c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C22H28O7/c1-23-17-9-13(10-18(24-2)21(17)27-5)15-7-8-16(29-15)14-11-19(25-3)22(28-6)20(12-14)26-4/h9-12,15-16H,7-8H2,1-6H3/t15-,16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	268	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rhone-Poulenc Sante Curated by PDSP Ki Database									J Pharmacol Exp Ther 252: 1221-7 (1990) BindingDB Entry DOI: 10.7270/Q2JW8CC2
					More data for this Ligand-Target Pair
Platelet activating factor receptor (Cavia porcellus)	BDBM50002831 ((2R,5R)-2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahyd...) Show SMILES COc1cc(cc(OC)c1OC)[C@@H]1CC[C@H](O1)c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C22H28O7/c1-23-17-9-13(10-18(24-2)21(17)27-5)15-7-8-16(29-15)14-11-19(25-3)22(28-6)20(12-14)26-4/h9-12,15-16H,7-8H2,1-6H3/t15-,16-/m0/s1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of PAF receptor binding to rabbit platelet plasma membranes				J Med Chem 29: 1917-21 (1986) BindingDB Entry DOI: 10.7270/Q2X63KZS
					More data for this Ligand-Target Pair
Platelet activating factor receptor (Homo sapiens (Human))	BDBM50002831 ((2R,5R)-2,5-Bis-(3,4,5-trimethoxy-phenyl)-tetrahyd...) Show SMILES COc1cc(cc(OC)c1OC)[C@@H]1CC[C@H](O1)c1cc(OC)c(OC)c(OC)c1 Show InChI InChI=1S/C22H28O7/c1-23-17-9-13(10-18(24-2)21(17)27-5)15-7-8-16(29-15)14-11-19(25-3)22(28-6)20(12-14)26-4/h9-12,15-16H,7-8H2,1-6H3/t15-,16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by ChEMBL					Assay Description Concentration required to cause 50% inhibition of platelet activating factor (PAF)-induced platelet aggregation of human platelet rich plasma when ch...				J Med Chem 34: 457-61 (1991) BindingDB Entry DOI: 10.7270/Q2BV7FK0
					More data for this Ligand-Target Pair