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BDBM50002866 CHEMBL266741

SMILES: Cc1oc(nc1CCOc1ccc(C[C@@H](CNc2ccccn2)Nc2ccccc2C(=O)c2ccccc2)cc1)-c1ccccc1

InChI Key: InChIKey=CZEUGVSJKYVCFU-YTTGMZPUSA-N

Data: 1 KI

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50002866   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50002866
PNG
(CHEMBL266741)
Show SMILES Cc1oc(nc1CCOc1ccc(C[C@@H](CNc2ccccn2)Nc2ccccc2C(=O)c2ccccc2)cc1)-c1ccccc1
Show InChI InChI=1S/C39H36N4O3/c1-28-35(43-39(46-28)31-14-6-3-7-15-31)23-25-45-33-21-19-29(20-22-33)26-32(27-41-37-18-10-11-24-40-37)42-36-17-9-8-16-34(36)38(44)30-12-4-2-5-13-30/h2-22,24,32,42H,23,25-27H2,1H3,(H,40,41)/t32-/m0/s1
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Article
PubMed
166n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Displacement of [3H]BRL49653 from PPARgamma by scintillation proximity assay


Bioorg Med Chem Lett 17: 3916-20 (2007)

Checked by Author
Article DOI: 10.1016/j.bmcl.2007.04.111
BindingDB Entry DOI: 10.7270/Q2R49S33
More data for this
Ligand-Target Pair