BDBM50002957 CHEMBL398028
SMILES: O=C(NCCCN1CCOCC1)[C@@H](Cc1ccccc1)NC(=O)C1(Cc2ccccc2C1)NC(=O)c1cc2ccccc2s1
InChI Key: InChIKey=HBFPLRNQVZTHGZ-GDLZYMKVSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neurokinin 2 receptor (Homo sapiens (Human)) | BDBM50002957 (CHEMBL398028) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Menarini Ricerche SpA Curated by ChEMBL | Assay Description Displacement of [125I]NKA from human NK2 expressed in CHO-K1 cells | Bioorg Med Chem Lett 17: 4841-4 (2007) Checked by Author Article DOI: 10.1016/j.bmcl.2007.06.053 BindingDB Entry DOI: 10.7270/Q22F7PXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neurokinin 2 receptor (GUINEA PIG) | BDBM50002957 (CHEMBL398028) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Menarini Ricerche SpA Curated by ChEMBL | Assay Description Agonist activity at NK2 receptor in guinea pig smooth muscle | Bioorg Med Chem Lett 17: 4841-4 (2007) Checked by Author Article DOI: 10.1016/j.bmcl.2007.06.053 BindingDB Entry DOI: 10.7270/Q22F7PXR | |||||||||||
More data for this Ligand-Target Pair |