BDBM50003040 CHEMBL122860::Dimethyl-[2-(1,6,7,8-tetrahydro-pyrano[2,3-f]indol-3-yl)-ethyl]-amine

SMILES: CN(C)CCc1c[nH]c2cc3CCCOc3cc12

InChI Key: InChIKey=JLWIAKOXJGKMDU-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50003040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50003040 (CHEMBL122860 | Dimethyl-[2-(1,6,7,8-tetrahydro-pyr...) Show SMILES CN(C)CCc1c[nH]c2cc3CCCOc3cc12 Show InChI InChI=1S/C15H20N2O/c1-17(2)6-5-12-10-16-14-8-11-4-3-7-18-15(11)9-13(12)14/h8-10,16H,3-7H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc. Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1C receptor in pig choroid plexus using [3H]-mesulergine as radioligand				J Med Chem 35: 3625-32 (1992) BindingDB Entry DOI: 10.7270/Q2125RK7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50003040 (CHEMBL122860 | Dimethyl-[2-(1,6,7,8-tetrahydro-pyr...) Show SMILES CN(C)CCc1c[nH]c2cc3CCCOc3cc12 Show InChI InChI=1S/C15H20N2O/c1-17(2)6-5-12-10-16-14-8-11-4-3-7-18-15(11)9-13(12)14/h8-10,16H,3-7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc. Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1D receptor in bovine caudate using [3H]- serotonin as radioligand				J Med Chem 35: 3625-32 (1992) BindingDB Entry DOI: 10.7270/Q2125RK7
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50003040 (CHEMBL122860 | Dimethyl-[2-(1,6,7,8-tetrahydro-pyr...) Show SMILES CN(C)CCc1c[nH]c2cc3CCCOc3cc12 Show InChI InChI=1S/C15H20N2O/c1-17(2)6-5-12-10-16-14-8-11-4-3-7-18-15(11)9-13(12)14/h8-10,16H,3-7H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc. Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [125I]DOI as radioligand				J Med Chem 35: 3625-32 (1992) BindingDB Entry DOI: 10.7270/Q2125RK7
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50003040 (CHEMBL122860 | Dimethyl-[2-(1,6,7,8-tetrahydro-pyr...) Show SMILES CN(C)CCc1c[nH]c2cc3CCCOc3cc12 Show InChI InChI=1S/C15H20N2O/c1-17(2)6-5-12-10-16-14-8-11-4-3-7-18-15(11)9-13(12)14/h8-10,16H,3-7H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc. Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity towards 5-hydroxytryptamine 2 receptor in rat anterior cortex using [3H]ketanserin as radioligand				J Med Chem 35: 3625-32 (1992) BindingDB Entry DOI: 10.7270/Q2125RK7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50003040 (CHEMBL122860 | Dimethyl-[2-(1,6,7,8-tetrahydro-pyr...) Show SMILES CN(C)CCc1c[nH]c2cc3CCCOc3cc12 Show InChI InChI=1S/C15H20N2O/c1-17(2)6-5-12-10-16-14-8-11-4-3-7-18-15(11)9-13(12)14/h8-10,16H,3-7H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc. Curated by ChEMBL					Assay Description Compound was evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat cortex using [3H]-8-OH-DPAT as radioligand				J Med Chem 35: 3625-32 (1992) BindingDB Entry DOI: 10.7270/Q2125RK7
					More data for this Ligand-Target Pair