BDBM50003575 CHEMBL3234893

SMILES: NC(=O)c1cc(sc1Nc1ccccc1)-c1ccccc1

InChI Key: InChIKey=IOQOXJYPPSTVRX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50003575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50003575 (CHEMBL3234893) Show SMILES NC(=O)c1cc(sc1Nc1ccccc1)-c1ccccc1 Show InChI InChI=1S/C17H14N2OS/c18-16(20)14-11-15(12-7-3-1-4-8-12)21-17(14)19-13-9-5-2-6-10-13/h1-11,19H,(H2,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of JAK3 (unknown origin)				Bioorg Med Chem Lett 24: 1968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.02.064 BindingDB Entry DOI: 10.7270/Q2CF9RM3
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50003575 (CHEMBL3234893) Show SMILES NC(=O)c1cc(sc1Nc1ccccc1)-c1ccccc1 Show InChI InChI=1S/C17H14N2OS/c18-16(20)14-11-15(12-7-3-1-4-8-12)21-17(14)19-13-9-5-2-6-10-13/h1-11,19H,(H2,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Bioorg Med Chem Lett 24: 1968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.02.064 BindingDB Entry DOI: 10.7270/Q2CF9RM3
					More data for this Ligand-Target Pair