BDBM50003683 CHEMBL513473

SMILES: Clc1ccc2c(NCCN3C(=O)C(=O)N(CC=C)C3=S)ccnc2c1

InChI Key: InChIKey=MWHMILGSQAUKLS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003683   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histidine-rich protein PFHRP-II (Plasmodium falciparum)	BDBM50003683 (CHEMBL513473) Show SMILES Clc1ccc2c(NCCN3C(=O)C(=O)N(CC=C)C3=S)ccnc2c1 Show InChI InChI=1S/C17H15ClN4O2S/c1-2-8-21-15(23)16(24)22(17(21)25)9-7-20-13-5-6-19-14-10-11(18)3-4-12(13)14/h2-6,10H,1,7-9H2,(H,19,20)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Antiplasmodial activity as inhibition of beta-hematin against Plasmodium yoelii N67 infected Swiss mice (Mus musculus) erythrocytes				Bioorg Med Chem Lett 19: 2570-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.026 BindingDB Entry DOI: 10.7270/Q2JD4Z8D
					More data for this Ligand-Target Pair