BDBM50003686 CHEMBL466436

SMILES: CCCCN1C(=O)C(=O)N(CCCNc2ccnc3cc(Cl)ccc23)C1=S

InChI Key: InChIKey=ISJMGIQVVVCJEY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003686   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histidine-rich protein PFHRP-II (Plasmodium falciparum)	BDBM50003686 (CHEMBL466436) Show SMILES CCCCN1C(=O)C(=O)N(CCCNc2ccnc3cc(Cl)ccc23)C1=S Show InChI InChI=1S/C19H21ClN4O2S/c1-2-3-10-23-17(25)18(26)24(19(23)27)11-4-8-21-15-7-9-22-16-12-13(20)5-6-14(15)16/h5-7,9,12H,2-4,8,10-11H2,1H3,(H,21,22)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Antiplasmodial activity as inhibition of beta-hematin against Plasmodium yoelii N67 infected Swiss mice (Mus musculus) erythrocytes				Bioorg Med Chem Lett 19: 2570-3 (2009) Article DOI: 10.1016/j.bmcl.2009.03.026 BindingDB Entry DOI: 10.7270/Q2JD4Z8D
					More data for this Ligand-Target Pair