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SMILES: CC1(C)CC(CSc2nc(c([nH]2)-c2ccccc2)-c2ccccc2)OC(=O)C1

InChI Key: InChIKey=IPFXAKYNHZILNT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003808   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sterol O-acyltransferase 1


(Rattus norvegicus)		BDBM50003808
PNG
(6-(4,5-Diphenyl-1H-imidazol-2-ylsulfanylmethyl)-4,...)
Show SMILES CC1(C)CC(CSc2nc(c([nH]2)-c2ccccc2)-c2ccccc2)OC(=O)C1
Show InChI InChI=1S/C23H24N2O2S/c1-23(2)13-18(27-19(26)14-23)15-28-22-24-20(16-9-5-3-6-10-16)21(25-22)17-11-7-4-8-12-17/h3-12,18H,13-15H2,1-2H3,(H,24,25)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 100n/an/an/an/an/an/a



Rhone-Poulenc Rorer

Curated by ChEMBL


Assay Description
Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsome

J Med Chem 35: 4384-92 (1992)


BindingDB Entry DOI: 10.7270/Q218374H
More data for this
Ligand-Target Pair