BDBM50003983 CHEMBL2180435

SMILES: C(Oc1nc(nc2cnccc12)-c1cccc(c1)-c1ncco1)c1ccncc1

InChI Key: InChIKey=NNDCGADZOHFNFL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003983   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50003983 (CHEMBL2180435) Show SMILES C(Oc1nc(nc2cnccc12)-c1cccc(c1)-c1ncco1)c1ccncc1 Show InChI InChI=1S/C22H15N5O2/c1-2-16(12-17(3-1)21-25-10-11-28-21)20-26-19-13-24-9-6-18(19)22(27-20)29-14-15-4-7-23-8-5-15/h1-13H,14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE10A by fluorescence polarization assay				J Med Chem 55: 7299-331 (2012) Article DOI: 10.1021/jm3004976 BindingDB Entry DOI: 10.7270/Q2C24XJK
					More data for this Ligand-Target Pair