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SMILES: NC[C@H]1CN(C(=O)C[C@@H]1c1cc(F)ccc1F)c1ccc2nnc(n2n1)C(F)(F)F

InChI Key: InChIKey=FMGTVKKOWLTXFH-ONGXEEELSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004096   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM50004096
PNG
(CHEMBL3236119)
Show SMILES NC[C@H]1CN(C(=O)C[C@@H]1c1cc(F)ccc1F)c1ccc2nnc(n2n1)C(F)(F)F |r|
Show InChI InChI=1S/C18H15F5N6O/c19-10-1-2-13(20)12(5-10)11-6-16(30)28(8-9(11)7-24)15-4-3-14-25-26-17(18(21,22)23)29(14)27-15/h1-5,9,11H,6-8,24H2/t9-,11-/m0/s1
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MMDB

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Article
PubMed
n/an/a 79n/an/an/an/an/an/a



M.S. University of Baroda

Curated by ChEMBL


Assay Description
Inhibition of human DPP-4 expressed in baculovirus expression system using H-Gly-Pro-AMC as substrate after 30 mins by fluorometric analysis

Bioorg Med Chem Lett 24: 1918-22 (2014)


Article DOI: 10.1016/j.bmcl.2014.03.009
BindingDB Entry DOI: 10.7270/Q2G73G7F
More data for this
Ligand-Target Pair