BDBM50004103 CHEMBL3236126

SMILES: NC[C@H]1CN(CCc2ccc3OCOc3c2)C(=O)C[C@@H]1c1cc(F)c(F)cc1F

InChI Key: InChIKey=RCWJJEHGGXFFFW-KBPBESRZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004103   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50004103 (CHEMBL3236126) Show SMILES NC[C@H]1CN(CCc2ccc3OCOc3c2)C(=O)C[C@@H]1c1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C21H21F3N2O3/c22-16-8-18(24)17(23)6-15(16)14-7-21(27)26(10-13(14)9-25)4-3-12-1-2-19-20(5-12)29-11-28-19/h1-2,5-6,8,13-14H,3-4,7,9-11,25H2/t13-,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
M.S. University of Baroda Curated by ChEMBL					Assay Description Inhibition of human DPP-4 expressed in baculovirus expression system using H-Gly-Pro-AMC as substrate after 30 mins by fluorometric analysis				Bioorg Med Chem Lett 24: 1918-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.009 BindingDB Entry DOI: 10.7270/Q2G73G7F
					More data for this Ligand-Target Pair