BDBM50004130 CHEMBL3236131

SMILES: NC[C@H]1CN(CCc2ccc3OCOc3c2)C(=O)C[C@@H]1c1ccc(Cl)cc1Cl

InChI Key: InChIKey=NDSVZMNIJRLJLO-YOEHRIQHSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50004130 (CHEMBL3236131) Show SMILES NC[C@H]1CN(CCc2ccc3OCOc3c2)C(=O)C[C@@H]1c1ccc(Cl)cc1Cl |r| Show InChI InChI=1S/C21H22Cl2N2O3/c22-15-2-3-16(18(23)8-15)17-9-21(26)25(11-14(17)10-24)6-5-13-1-4-19-20(7-13)28-12-27-19/h1-4,7-8,14,17H,5-6,9-12,24H2/t14-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
M.S. University of Baroda Curated by ChEMBL					Assay Description Inhibition of human DPP-4 expressed in baculovirus expression system using H-Gly-Pro-AMC as substrate after 30 mins by fluorometric analysis				Bioorg Med Chem Lett 24: 1918-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.009 BindingDB Entry DOI: 10.7270/Q2G73G7F
					More data for this Ligand-Target Pair