BDBM50004172 CHEMBL544763::Sulfamic acid 2-(4-imidazol-1-yl-phenoxy)-ethyl ester; hydrochloride
SMILES: NS(=O)(=O)OCCOc1ccc(cc1)-n1ccnc1
InChI Key: InChIKey=UPUSYKDVXRVZRB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50004172 (CHEMBL544763 | Sulfamic acid 2-(4-imidazol-1-yl-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier II Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase II | J Med Chem 46: 2197-204 (2003) Article DOI: 10.1021/jm021124k BindingDB Entry DOI: 10.7270/Q28P617T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM50004172 (CHEMBL544763 | Sulfamic acid 2-(4-imidazol-1-yl-ph...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier II Curated by ChEMBL | Assay Description Inhibitory concentration against catalytic domain of human cloned carbonic anhydrase IX. | J Med Chem 46: 2197-204 (2003) Article DOI: 10.1021/jm021124k BindingDB Entry DOI: 10.7270/Q28P617T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50004172 (CHEMBL544763 | Sulfamic acid 2-(4-imidazol-1-yl-ph...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Montpellier II Curated by ChEMBL | Assay Description Inhibition of human recombinant carbonic anhydrase I | J Med Chem 46: 2197-204 (2003) Article DOI: 10.1021/jm021124k BindingDB Entry DOI: 10.7270/Q28P617T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 6 (Bos taurus) | BDBM50004172 (CHEMBL544763 | Sulfamic acid 2-(4-imidazol-1-yl-ph...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
A.H. Robins Company Curated by ChEMBL | Assay Description Bovine erythrocyte carbonic anhydrase inhibitory activity of the compound. | J Med Chem 35: 4790-4 (1992) BindingDB Entry DOI: 10.7270/Q2MS3W1G | |||||||||||
More data for this Ligand-Target Pair |