BDBM50004528 CHEMBL2216834

SMILES: Clc1ccc(-c2nc(sc2-c2nnc[nH]2)N2CCOCC2)c(Cl)c1

InChI Key: InChIKey=GTDMVDLUZFYXJL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004528   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50004528 (CHEMBL2216834) Show SMILES Clc1ccc(-c2nc(sc2-c2nnc[nH]2)N2CCOCC2)c(Cl)c1 Show InChI InChI=1S/C15H13Cl2N5OS/c16-9-1-2-10(11(17)7-9)12-13(14-18-8-19-21-14)24-15(20-12)22-3-5-23-6-4-22/h1-2,7-8H,3-6H2,(H,18,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta				J Med Chem 55: 8559-81 (2012) Article DOI: 10.1021/jm300847w BindingDB Entry DOI: 10.7270/Q2SN0B47
					More data for this Ligand-Target Pair