BDBM50004541 CHEMBL2216851

SMILES: COc1ccc(cc1F)-c1nn(C)c2nc(N)nc(NCc3ccccc3)c12

InChI Key: InChIKey=ZDSDDXMAPQKSTN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004541   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50004541 (CHEMBL2216851) Show SMILES COc1ccc(cc1F)-c1nn(C)c2nc(N)nc(NCc3ccccc3)c12 Show InChI InChI=1S/C20H19FN6O/c1-27-19-16(17(26-27)13-8-9-15(28-2)14(21)10-13)18(24-20(22)25-19)23-11-12-6-4-3-5-7-12/h3-10H,11H2,1-2H3,(H3,22,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta				J Med Chem 55: 8559-81 (2012) Article DOI: 10.1021/jm300847w BindingDB Entry DOI: 10.7270/Q2SN0B47
					More data for this Ligand-Target Pair